2018 · Designed by Edmund McMillen · Published by Studio 71
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Based on the roguelike video game, Four Souls is a chaotic multiplayer card game about sacrifice, betrayal, and hoarding. Players take turns slaying monsters to collect items and souls, with backstabbing encouraged — first to four souls at the end of their turn wins.
Stuff your runs with 100 new cards packed with fresh Treasures, Loots, Monsters, and four brand-new starting characters — including the Whore of Babylon, Guppy, Bumbo, and Dark Judas. Shuffle them into the base game for wilder, weirder sessions of the irreverent dungeon-looting card game. · 2019
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A mini-expansion for The Binding of Isaac: Four Souls drawing on characters and themes from Edmund McMillen's other games, created by McMillen himself to mark the game's anniversary.
A community-made supplement to The Binding of Isaac: Four Souls, its cards submitted by fans and hand-picked by creator Edmund McMillen to fold the best of them into your collection.
A celebration of The Binding of Isaac's tenth anniversary, journeying through every era of Isaac's story and supplementing any Four Souls collection with cards spanning the franchise's history.
Fifteen new cards with guest artwork, made for the sixth anniversary of Four Souls.
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